CLSI C40

Measurement Procedures for the Determination of Lead in Whole Blood, 3rd Edition

CLSI C40 provides recommendations on the measurement of lead (Pb) in whole blood, including specimen collection procedures and determination of Pb by graphite furnace atomic absorption spectrometry, anodic stripping voltammetry (based on disposable screen-printed electrode technologies), and inductively coupled plasma mass spectrometry. It also includes quality assurance and quality control guidance and information on proficiency testing programs and laboratory certification.

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Chairholder: Patrick J. Parsons, PhD, CChem, FRSC

Date of Publication: April 18, 2024

Order Code PDF: CLSI C40Ed3E
ISBN Number: 978-1-68440-219-9

Order Code Print: CLSI C40Ed3
ISBN Number: 978-1-68440-218-2

Edition: Third

Pages: 128

CLSI C40 Additional Details

A guideline for global application developed through the Clinical and Laboratory Standards Institute consensus process.

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CLSI C40 Abstract

Clinical and Laboratory Standards Institute C40—Measurement Procedures for the Determination of Lead in Whole Blood is intended for use by members of the medical laboratory community involved in the determination of lead (Pb) in blood, as well as by personnel involved in specimen collection. This guideline discusses the clinical significance of blood lead (BPb) measurements; specimen collection; and Pb determination by graphite furnace atomic absorption spectrometry, anodic stripping voltammetry (based on disposable screen-printed electrode technologies), and inductively coupled plasma mass spectrometry. It also discusses reference materials, QC procedures, and laboratory policies for BPb testing.