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Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi, 3rd Edition

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CLSI M38

Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi, 3rd Edition

This standard includes antifungal agent selection, preparation of antifungal stock solutions and dilutions for testing, test procedure implementation and interpretation, and quality control requirements for susceptibility testing of filamentous fungi (moulds) that cause invasive and cutaneous fungal infections.

Supplemental tables for M38 are published in CLSI document M38M51S.

This edition of the document was corrected in September 2018. Read the full correction notice here, and learn more about our corrections process here. 

This document is available in electronic format only.

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Details

Chairholder: Barbara D. Alexander, MD, MHS

Date of Publication: November 30, 2017

Order Code PDF: CLSI M38Ed3E
ISBN Number: 1-56238-831-2

Order Code Print: print not available

Edition: Third

Pages: 62

CLSI M38 Abstract

Clinical and Laboratory Standards Institute standard M38—Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi describes a method for testing the susceptibility to antifungal agents of filamentous fungi (nondermatophyte and dermatophyte moulds) that cause invasive and/or cutaneous fungal infections. Antifungal agent selection, preparation of antifungal stock solutions and dilutions for testing, test procedure implementation and interpretation, and the purpose and implementation of QC procedures are discussed. A careful examination of manufacturer and user responsibilities in QC is also presented. In addition, a brief discussion regarding newly defined epidemiological cutoff values for certain Aspergillus spp. and species complexes are included.

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