CLSI Publishes New Chemistry Document C34—Sweat Testing: Specimen Collection and Quantitative Chloride Analysis

Wayne, Pennsylvania, USA—The Clinical and Laboratory Standards Institute has published C34—Sweat Testing: Specimen Collection and Quantitative Chloride Analysis. C34 describes methods for performing sweat testing for cystic fibrosis diagnosis. Sweat stimulation, collection, and quantitative measurement of sweat chloride are described, along with results evaluation and reporting, quality assurance, and method validation.

C34 contains helpful appendixes with information on:

• Sweat collection on gauze or filter paper and chloride analysis using a digital chloridometer with individual titration vials.
• Sweat collection into coiled tubing and chloride analysis using a digital chloridometer with individual titration vials.
• Clinical indications for sweat testing.
• Pilocarpine nitrate concentration.
• Current density.
• Reported diseases or conditions other than cystic fibrosis associated with an elevated sweat electrolyte concentration.  

 For more information about C34, contact Patrick McGinn at pmcginn@clsi.org or +1.484.588.5933.   

   

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