CLSI AST Rationale Documents - PDF (Free)

Using the CLSI voluntary consensus process, the Subcommittee on Antimicrobial Susceptibility Testing develops standards that promote accurate antimicrobial susceptibility testing (AST) and appropriate reporting. The subcommittee reviews data from various sources and studies (eg, in vitro, pharmacokinetic-pharmacodynamic, and clinical studies) to establish antimicrobial susceptibility test methods, breakpoints, and quality control ranges.

It is important for medical laboratories, drug and device manufacturers, and regulatory and accreditation organizations to understand how AST breakpoints and interpretive categories are determined. To meet this need, CLSI has published rationale documents that provide the scientific reasons behind the subcommittee’s decisions, along with documentation of the standardized data and methods used to determine breakpoints.

Interested in the latest AST information from CLSI? Visit clsi.org/ast2021.

This package includes: